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{"fact":"A cat almost never meows at another cat, mostly just humans. Cats typically will spit, purr, and hiss at other cats.","length":116}
{"slip": { "id": 110, "advice": "Give up your seat for someone who needs it."}}
{"type":"standard","title":"Metabolic flux analysis","displaytitle":"Metabolic flux analysis","namespace":{"id":0,"text":""},"wikibase_item":"Q6822342","titles":{"canonical":"Metabolic_flux_analysis","normalized":"Metabolic flux analysis","display":"Metabolic flux analysis"},"pageid":10756580,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/6/6f/Major_metabolic_fluxes_in_neuron-astrocyte_coupling_for_resting_conditions.png/330px-Major_metabolic_fluxes_in_neuron-astrocyte_coupling_for_resting_conditions.png","width":320,"height":222},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/6/6f/Major_metabolic_fluxes_in_neuron-astrocyte_coupling_for_resting_conditions.png","width":1024,"height":710},"lang":"en","dir":"ltr","revision":"1197412676","tid":"91389063-b785-11ee-8acb-b514966165bb","timestamp":"2024-01-20T11:17:59Z","description":"Experimental fluxomics technique","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/Metabolic_flux_analysis","revisions":"https://en.wikipedia.org/wiki/Metabolic_flux_analysis?action=history","edit":"https://en.wikipedia.org/wiki/Metabolic_flux_analysis?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:Metabolic_flux_analysis"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/Metabolic_flux_analysis","revisions":"https://en.m.wikipedia.org/wiki/Special:History/Metabolic_flux_analysis","edit":"https://en.m.wikipedia.org/wiki/Metabolic_flux_analysis?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:Metabolic_flux_analysis"}},"extract":"Metabolic flux analysis (MFA) is an experimental fluxomics technique used to examine production and consumption rates of metabolites in a biological system. At an intracellular level, it allows for the quantification of metabolic fluxes, thereby elucidating the central metabolism of the cell. Various methods of MFA, including isotopically stationary metabolic flux analysis, isotopically non-stationary metabolic flux analysis, and thermodynamics-based metabolic flux analysis, can be coupled with stoichiometric models of metabolism and mass spectrometry methods with isotopic mass resolution to elucidate the transfer of moieties containing isotopic tracers from one metabolite into another and derive information about the metabolic network. Metabolic flux analysis (MFA) has many applications such as determining the limits on the ability of a biological system to produce a biochemical such as ethanol, predicting the response to gene knockout, and guiding the identification of bottleneck enzymes in metabolic networks for metabolic engineering efforts.","extract_html":"
Metabolic flux analysis (MFA) is an experimental fluxomics technique used to examine production and consumption rates of metabolites in a biological system. At an intracellular level, it allows for the quantification of metabolic fluxes, thereby elucidating the central metabolism of the cell. Various methods of MFA, including isotopically stationary metabolic flux analysis, isotopically non-stationary metabolic flux analysis, and thermodynamics-based metabolic flux analysis, can be coupled with stoichiometric models of metabolism and mass spectrometry methods with isotopic mass resolution to elucidate the transfer of moieties containing isotopic tracers from one metabolite into another and derive information about the metabolic network. Metabolic flux analysis (MFA) has many applications such as determining the limits on the ability of a biological system to produce a biochemical such as ethanol, predicting the response to gene knockout, and guiding the identification of bottleneck enzymes in metabolic networks for metabolic engineering efforts.
"}